Publication: Shed NKG2D ligand boosts NK cell immunity.

Published in: Cell Res 2015 Jun; 25(6): 651-2

Authors: Narni-Mancinelli E, Vivier E

Summary

Ligands for natural killer (NK) cell activating receptors can be released from tumor cells and are believed to promote tumor growth by acting as decoys for effector lymphocytes. In a recent paper published in Science, Deng et al. report another scenario in which a shed form of the MULT1 mouse NKG2D ligand boosts NK cell functions.

Link to Pubmed [PMID] – 25849247

Link to DOI – 10.1038/cr.2015.41