Publication: Regulatory natural killer cells: new players in the IL-10 anti-inflammatory response.

Published in: Cell Host and Microbe, 2009, 6 (6), pp.493-5. ⟨10.1016/j.chom.2009.12.001⟩

Authors: Eric Vivier, Sophie Ugolini

Summary

Natural Killer (NK) cells boost immune defense via their cytolytic activity and their capacity to produce interferon-gamma. Now Perona-Wright et al. (2009), in this issue of Cell Host & Microbe, show that NK cells can also dampen immune responses to diverse pathogens via secretion of the anti-inflammatory cytokine interleukin-10. Remarkably, this immunosuppressive activity only occurs during systemic infections.

Link to Pubmed [PMID] – 20006835

Link to HAL – hal-00502729

Link to DOI – 10.1016/j.chom.2009.12.001