Good news, bad news for missing-self recognition by NK cells: autoimmune control but viral evasion.

Theme

Nectin-4 is a new histological and serological tumor associated marker for breast cancer.

The C-MYB locus is involved in chromosomal translocation and genomic duplications in human T-cell acute leukemia (T-ALL) – the translocation defining a new T-ALL subtype in very young children.

Published in: Immunity, 2007, 26 (5), pp.549-51. ⟨10.1016/j.immuni.2007.05.006⟩

Authors: Eric Vivier, François Romagné

Summary

In this issue of Immunity, Voigt et al. (2007) and Lu et al. (2007) extend the understanding of the consequences of missing-self recognition in immune evasion and immune cell regulation via NKRP-1 and CD94-NKG2A inhibitory receptors, respectively.

Link to HAL – hal-00165506

Link to DOI – 10.1016/j.immuni.2007.05.006