Publication: Interaction between GUVs and catanionic nanocontainers: new insight into spontaneous membrane fusion.

Published in: Chem Commun (Camb) 2012 Jul; 48(53): 6648-50

Authors: Mauroy C, Castagnos P, Blache MC, Teissié J, Rico-Lattes I, Rols MP, Blanzat M

Summary

Spontaneous receptor-free membrane fusion with pure lipid systems, used as a cell membrane model, is demonstrated with easy-to-handle lactose-derived catanionic vesicles. This fusion, mediated and controlled by phospholipids, emphasizes the great value of these nanovesicles for enhanced direct cytosolic drug delivery without the shortcomings linked with endocytic pathways.

Link to Pubmed [PMID] – 22634609

Link to DOI – 10.1039/c2cc32093b