Published in: Nature Immunology, 2020, 21 (7), pp.700-703. ⟨10.1038/s41590-020-0687-4⟩
Authors: Stephanie Vargas Aguilar, Oscar Aguilar, Rhys Allan, El Ad David Amir, Veronique Angeli, Maxim N. Artyomov, Natasha Asinovski, Jilian Astarita, K. Frank Austen, Geetika Bajpai, Nora Barrett, Alev Baysoy, Christophe Benoist ✉, Angelique Bellemare-Pelletier, Brad Berg, Adam Best, Natalie Bezman, David Blair, Julie M. Blander, Milena Bogunovic, Patrick Brennan, Michael Brenner, Brian Brown, Matthew Buechler, Jason Buenrostro, Maria Acebes Casanova, Kyunghee Choi, Andrew Chow, Aleksey Chudnovskiy, Daniela Cipoletta, Nadia Cohen, James J. Collins, Marco Colonna, Alison Cook, James Costello, Viviana Cremasco, Ty Crowl, Karine Crozat, Richard Cruse, June D’angelo, Marc Dalod, Scott Davi, Cagatay Demiralp, Tianda Deng, Jigar V. Desa, Fiona Desland, Maxime Dhainaut, Jiarui Ding, Andrew Doedens, Claudia Dominguez, Graeme Doran, Regine Dress, Michael Dustin, Daniel Dwyer, Ivan Dzhagalov, Kutlu Elpek, Ayla Ergun, Jef Ericson, Eunice Esomonu, Keke Fairfax, Anne Fletcher, Michela Frascoli, Anja Fuchs, Anastasiia Gainullina, Shani Gal-Oz, Michael Gallagher, Emmanuel Gautier, Roi Gazit, Sophie Gibbings, Matthieu Giraud, Florent Ginhoux, Ananda Goldrath, Dagmar Gotthardt, Daniel Gray, Melanie Greter, Ricardo Grieshaber-Bouyer, Martin Guilliams, Sara Haidermota, Randy Hardy, Daigo Hashimoto, Julie Helft, Deborah Hendricks, Tracy Heng, Jonathan Hill, Gordon Hyatt, Juliana Idoyaga, Claudia Jakubzick, Jessica Jarjoura, Daniel Jepson, Baosen Jia, Radu Jianu, Tim Johanson, Vladimir Jojic, Stefan Jordan, Yosuke Kamimura, Veronica Kana, Joonsoo Kang, Varun Kapoor, Ephriam Kenigsberg, Andrew Kent, Charles Kim, Edy Kim, Francis Kim, Joel Kim, Kiwook Kim, Evgeny Kiner, Jamie Knell, Daphne Koller, Larry Kozinn, Karen Krchma, Taras Kreslavsky, Mitchell Kronenberg, Wing-Hong Kwan, David Laidlaw, Viola Lam, Lewis Lanier, Catherine Laplace, Caleb Lareau, Yonit Lavin, Kory J. Lavine, Andrew Leader, Marylene Leboeuf, Jacob Lee, Jisu Lee, Bo Li, Hu Li, Yuesheng Li, Michail S. Lionakis, Herve Luche, Lydia Lynch, Assaf Magen, Barbara Maier, Deepali Malhotra, Nidhi Malhotra, Marie Malissen, Alexandra Maslova, Diane Mathis, Adelle Mcfarland, Miriam Merad, Etienne Meunier, Jennifer Miller, Justin Milner, Michael Mingueneau, Gundula Min-Oo, Paul Monach, Devapregasan Moodley, Arthur Mortha, Maelig Morvan, Sara Mostafavi, Soren Muller, Christoph Muus, Tsukasa Nabekura, Tata Nageswara Rao, Vipin Narang, Kavitha Narayan, Hadas Ner-Gaon, Quyhn Nguyen, Peter A. Nigrovic, German Novakovsky, Stephan Nutt, Kayla Omilusik, Adriana Ortiz-Lopez, Helena Paidassi, Henry Paik, Michio Painter, Mallory Paynich, Vincent Peng, Marc Potempa, Rachana Pradhan, Jeremy Price, Yilin Qi, Yiqing Qi, Sara Quon, Ricardo Ramirez, Deepshika Ramanan, Gwendalyn Randolph, Aviv Regev, Andrew Rhoads, Michelle Robinette, Samuel Rose, Derrick Rossi, Katie Rothamel, Ravi Sachidanandam, Priyanka Sathe, Charlotte Scott, Kumba Seddu, Peter See, Alexey Sergushichev, Laura Shaw, Tal Shay, Avishai Shemesh, Susan Shinton, Justin Shyer, Michael Sieweke, Chris Smillie, Lotte Spel, Nick Spidale, Giuseppina Stifano, Ayshwarya Subramanian, Joseph Sun, Katelyn Sylvia, Julie Tellier, Sébastien This, Elena Tomasello, Helena Todorov, Shannon Turley, Brinda Vijaykumar, Amy Wagers, Ei Wakamatsu, Chendi Wang, Peter L. Wang, Aleksandra Wroblewska, Jun Wu, Edward Yang, Liang Yang, Aldrin Yim, Lim Sheau Yng, Hideyuki Yoshida, Bingfei Yu, Yan Zhou, Yanan Zhu, Caroline Ziemkiewicz
Summary
700 comment | SERIES ImmGen at 15 Nature Immunology’s 20 th anniversary is a good opportunity to reminisce about the ImmGen collective endeavor-its goals, successes and horror stories-and the group’s exploration of various modes of scientific publishing. The Immunological Genome Project T he Immunological Genome Project (ImmGen) is a collaborative group of immunology and computational biology laboratories that perform a thorough dissection of gene expression and its regulation in the immune system of the mouse. This activity first centered on mRNA expression and then expanded to microRNA (miRNA), chromatin structure, nuclear organization and protein-RNA relationships. Shared protocols, data generation and QC pipelines have yielded data that can be directly compared from >250 stem, lymphoid and myeloid cell types, at baseline or under challenge. The group develops and applies computational tools to decipher regulatory connections and transcriptional control. From its inception, data generated by ImmGen were meant to be a public resource, and they can be accessed through dedicated web and smartphone platforms that use interactive graphic displays that make the results intuitive to users.
Link to Pubmed [PMID] – 32577013
Link to HAL – hal-03007523
Link to DOI – 10.1038/s41590-020-0687-4