Distinct t(7;9)(q34;q32) breakpoints in healthy individuals and individuals with T-ALL.

Theme

Dendritic cell responses to early murine cytomegalovirus infection: subset functional specialization and differential regulation by interferon alpha/beta.

Expression of a soluble and activatable form of bovine procarboxypeptidase A in Escherichia coli.

Published in: Nat Genet 2003 Mar; 33(3): 342-4

Authors: Marculescu R, Vanura K, Le T, Simon P, Jäger U, Nadel B

Summary

After V(D)J-mediated translocations, signal joints are retained on one of the derivative chromosomes. We report here that such signal joints are highly reactive and constitute unstable genomic elements with potential oncogenic properties.

Link to Pubmed [PMID] – 12567187