Project: Epic-SCENITH: regulators of metabolism and epigenetics in glioblastoma-associated myeloid cells

About

Duration: 2021–2025.
Partners & funding amounts: APHM/La Timone (E. Tabouret); amount for team: €325k.
Responsibilities: PI–coordinator (only beneficiary)
Theme & content of work: Develops Epic-SCENITH to map how early metabolic programs in GBM myeloid cells imprint epigenetic states and durable dysfunction, integrating in-vivo imaging with ex-vivo multi-omics for biomarker and target discovery.
Scope & impact: Foundational human method; diagnosis/stratification markers for GBM; transferable to AML and sepsis longitudinal cohorts.