Sophie UGOLINI
About
– Research Director at Inserm
– Team Director Neural regulation of immunity at the Marseille-Luminy Immunology Center
– Co-founder and scientific director of the start-up Temper Bio
Sophie Ugolini is a biologist and immunologist by training, recognized for her major contributions to research in the field of immunity. A research director at the French National Institute of Health and Medical Research (INSERM) since 2012, she leads the “Neural Regulation of Immunity” team at the Marseille-Luminy Immunology Center (CIML). Since receiving her doctorate in 1998, Sophie Ugolini has devoted her career to exploring the complex mechanisms that govern the immune response, particularly in the context of infections and cancers.
Her laboratory takes a multidisciplinary approach, linking immunology and neuroscience to better understand how the nervous system is involved in regulating inflammatory and immune responses. Thanks to significant funding from the European Research Council (ERC) and the Bettencourt Schueller Foundation through the Impulscience program, Sophie Ugolini explores the role of hormones and neuropeptides produced by the neuroendocrine system in regulating inflammation and tissue repair.
Her research has led to significant discoveries that open the way to new therapeutic perspectives, particularly for the treatment of autoimmune and inflammatory diseases. The development of new drugs in this field is at the heart of the activities of Temper Bio, a biotechnology company she co-founded.
Sophie Ugolini is a member of the Scientific Council of the Parliamentary Office for the Evaluation of Scientific and Technological Choices (OPECST). She has been a member of the Scientific Council of INSERM and the Fondation pour la Recherche Médicale (FRM). In addition to her numerous institutional responsibilities, Sophie Ugolini plays an active role in scientific evaluation at the national and international levels. She is regularly consulted as an expert by various research agencies and scientific committees, and contributes to shaping research policies in France and Europe. Furthermore, her expertise is recognized through her publishing activities in major scientific journals, thus strengthening her influence in the fields of immunology and neuroscience.
Sophie Ugolini's work is published in prestigious journals such as Nature And Science, and have been awarded several prestigious scientific prizes. She notably received the Dandrimont-Bénicourt Prize from the Institut de France in 2011, the INSERM Research Prize in 2012, and the Duquesne Prize from the Ligue contre le cancer in 2013, attesting to the impact of her contributions on the scientific community.
Projects
Project: T2DRGMacPain Obesity is a major factor in metabolic disorders such as type 2 diabetes. Dysfunction of […]
Nerve fibers are increasingly emerging as key players in the tumor microenvironment, capable of modulating […]
The host response to pathogens is orchestrated by the immune system and the nervous system, both present in […]
We have demonstrated that the neurokine TAFA4, produced by sensory neurons in the skin, can promote tissue repair […]
Beyond the pain perception processes that are induced in the event of injury or infection of the […]
Les macrophages résidents des tissus jouent un rôle fondamental dans l’homéostasie tissulaire et sa régénération après lésion. Dans un modèle […]