Login
Search
Theme

Members

Hai-Tao HE
Research Director
Marie DESSARD
PhD student
Anthony FORMISANO
Study Engineer
Xiao-Jun GUO
Senior lecturer
Yannick HAMON
Research Officer
Thibault JEANSON
Study Engineer
Marie MALISSEN
Research Director
Sophie PANIGOT
PhD student
Bernard MALISSEN
Research Director
Didier MARGUET
Research Director

About

The team's research program aims to decipher the molecular mechanisms of T cell activation, a central process in adaptive immunity. To achieve this, it adopts a systemic and interdisciplinary approach combining biophysics, biophotonics, proteomics, and genetic engineering to explore signaling dynamics, from the nanoscale to the whole-organism scale. The goal is to understand how early signals influence short- and medium-term cellular decisions, and thus improve the rational design of immunotherapies.

Our program is structured around three main axes.

A. Biophysics of transmembrane signaling (Leaders: HT He & Y Hamon)

  • Membrane physicochemistry and signalosome formation. During the interaction between the TCR and the pMHC complex, the T cell membrane undergoes rapid remodeling. This phenomenon promotes the formation of signalosomes, protein complexes essential for signaling. The team uses advanced techniques such as FCS (fluorescence correlation spectroscopy), FLIM microscopy, and solvatochromic probes to study lipid order and membrane tension, two key parameters influencing signaling.
  • Role of ABC transporters (ABCA1/ABCG1). These transporters regulate cholesterol efflux and influence membrane lipid composition. Their role is studied in the regulation of membrane mechanics, TCR configuration, intracellular trafficking, and T cell metabolism. Deficient mouse models and human patients allow us to explore their impact on immune signaling and function.

B. Integrative biology of T lymphocyte activation (Leaders: B Malissen & M Malissen)

  • T cell activation requires both antigen receptor (TCR)-mediated signals and the costimulatory molecule CD28. The cytosolic protein CARMIL2 enables activation of the transcription factor NF-kB through its ability to bind CD28 to the adaptor protein CARD11. The team developed mice expressing a mutation named Carmil2QE that mimics a mutation observed in human T cell malignancies. T cells from Carmil2QE mice contain preformed CARMIL2QE-CARD11 complexes in numbers comparable to those that assemble in T cells following CD28 activation. These preformed CARMIL2QE-CARD11 complexes also form in CD28-deficient mice. Unexpectedly, they induce most of the functions normally associated with CD28 activation in an antigen-dependent manner. The team showed that when tumor-specific T cells express Carmil2QE, they no longer require CD28 activation and thus escape inhibition by PD-1 and CTLA-4 inhibitors. The critical role of CARMIL2-CARD11 signals among those triggered by CD28 can therefore be exploited to induce potent solid tumor-specific T cell responses in the absence of CD28 ligands and immune checkpoint inhibitors.
  • IgG4-mediated disease (IgG4-RD). This fibroinflammatory autoimmune disease affects multiple organs. The LatY136F mouse model faithfully reproduces human pathological features. Using functional genetics and omics, the team explores the molecular and cellular mechanisms of the disease, with the aim of developing targeted therapies.

C. New technologies for the analysis of biomolecular interactions (Leader: Dr. Marguet)

  • Long-Range Electrodynamic Interactions (LEDIs). The European LINkS project explores the existence of long-range electrodynamic interactions between proteins through an interdisciplinary consortium. This project could revolutionize our understanding of cellular self-organization and the effects of electromagnetic fields on living organisms.
  • Development of FCS, SMLM, and polarimetry methods. The team is perfecting single-molecule microscopy (SMLM) and spectroscopy techniques to observe protein dynamics at high resolution. The integration of polarized fluorescence allows for structural images with information on membrane orientation.

Projects

Project
2025
LINkS -Long-range electrodynamic INteractions between proteins

Project: LINkS The LINkS project (EU FET-OPEN) aims to change the paradigms of self-organization of intracellular living matter, […]

Didier MARGUET
Project
2025
D2OX – Distribution and Dynamics of OXPHOS

Project: D2OX The interdisciplinary D2OX project is divided into three highly interconnected tasks to elucidate how the efficiency of OXPHOS complexes […]

Didier MARGUET

Publications

2025
Kondratowicz M, Wu A, Grela E, Raducka-Jaszul O, Luchowski R, Błaszczak E, Wójtowicz K, Hamon Y, G..., ABCA1 modifies plasma membrane organization of living cells., Biochim Biophys Acta Mol Cell Biol Lipids 2025 Oct; 1870(7): 159667.
2025
Aurélie Rossin, Giorgia Miloro, Laurent Gagnoux-Palacios, Sebastien Huault, Agnès Loubat, Anthony ..., Fas acts as a T cell co-stimulatory receptor both via a death domain-independent and dependent mechanism, 2025.
2025
Perez-Martin E, Beranger T, Bonnet L, Teppe F, Lisauskas A, Ikamas K, Vrouwe E, Floriani E, Katona G..., Unveiling long-range forces in light-harvesting proteins: Pivotal roles of temperature and light. Sci Adv 2025 May; 11(18): eadv0346.
2025
Mordzińska-Rak A, Verdeil G, Hamon Y, Błaszczak E, Trombik T, Dysregulation of cholesterol homeostasis in cancer pathogenesis. Cell Mol Life Sci 2025 Apr; 82(1): 168.
2025
Mailfert S, Djendli M, Fabre R, Marguet D, Bertaux N, Quality control maps: Real-time quantitative control of single-molecule localization microscopy data. Biophys J 2025 Apr; 124(7): 1132-1145.
2025
Tawbeh A, Gondcaille C, Saih FE, Raas Q, Loichot D, Hamon Y, Keime C, Benani A, Di Cara F, Cherkaoui..., Impaired peroxisomal beta-oxidation in microglia triggers oxidative stress and impacts neurons and oligodendrocytes. Front Mol Neurosci 2025; 18(): 1542938.
2024
Sébastien Mailfert, Meriem Djendli, Roxane Fabre, Didier Marguet, Nicolas Bertaux, QCM: real-time quantitative quality control of single-molecule localization microscopy acquisitions, 2024.
2024
Dessard M, Manneville JB, Berret JF, Cytoplasmic viscosity is a potential biomarker for metastatic breast cancer cells. Nanoscale Adv 2024 Mar; 6(6): 1727-1738.
2024
Parsons BD, Medina-Luna D, Scur M, Pinelli M, Gamage GS, Chilvers RA, Hamon Y, Ahmed IHI, Savary S, ..., Peroxisome deficiency underlies failures in hepatic immune cell development and antigen presentation in a severe Zellweger disease model. Cell Rep 2024 Feb; 43(2): 113744.
2023
Changting Li, Yannick Hamon, David Mazaud, Pamela Gonzalez Troncoso, Marie Dessard, Hai-Tao He, Chri..., Dia2 formin controls receptor activity by organizing plasma membrane lipid partitioning at the nanoscale, 2024.
2023
Marie Dessard, Jean-Baptiste Manneville, Jean-François Berret, Cytoplasmic Viscosity is a Potential Biomarker for Metastatic Breast Cancer Cells, <i>Nanoscale Advances</i>, 2023, 6 (6), pp.1727-1738. <a target="_blank" href="https://dx.doi.org/10.1101/2023.10.25.564072">⟨10.1101/2023.10.25.564072⟩</a>.
2023
Jaeger M, Anastasio A, Chamy L, Brustlein S, Vincentelli R, Durbesson F, Gigan J, Thépaut M, Char R..., Light-inducible T cell engages trigger, tune, and shape the activation of primary T cells. Proc Natl Acad Sci USA 2023 Sep; 120(39): e2302500120.
2023
Tawbeh A, Raas Q, Tahri-Joutey M, Keime C, Kaiser R, Trompier D, Nasser B, Bellanger E, Dessard M, H..., Immune response of BV-2 microglial cells is impacted by peroxisomal beta-oxidation. Front Mol Neurosci 2023; 16(): 1299314.
2023
Raas Q, Tawbeh A, Tahri-Joutey M, Gondcaille C, Keime C, Kaiser R, Trompier D, Nasser B, Leoni V, Be..., Peroxisomal defects in microglial cells induce a disease-associated microglial signature. Front Mol Neurosci 2023; 16(): 1170313.
2022
Porciello N, Cipria D, Masi G, Lanz AL, Milanetti E, Grottesi A, Howie D, Cobbold SP, Schermelleh L,..., Role of the membrane anchor in the regulation of Lck activity. J Biol Chem 2022 Dec; 298(12): 102663.
2022
Lechelon M, Meriguet Y, Gori M, Ruffenach S, Nardecchia I, Floriani E, Coquillat D, Teppe F, Mailfer..., Experimental evidence for long-distance electrodynamic intermolecular forces. Sci Adv 2022 Feb; 8(7): eabl5855.
2021
Raducka-Jaszul O, Wójtowicz K, Sikorski AF, Chimini G, Hamon Y, Trombik T, Molecular Diffusion of ABCA1 at the Cell Surface of Living Cells Assessed by svFCS. Membranes (Basel) 2021 Jun; 11(7): .
2021
Zak A, Merino-Cortés SV, Sadoun A, Mustapha F, Babataheri A, Dogniaux S, Dupré-Crochet S, Hudik E,..., Rapid viscoelastic changes are a hallmark of early leukocyte activation. Biophys J 2021 May; 120(9): 1692-1704.
2021
Sadoun A, Biarnes-Pelicot M, Ghesquiere-Dierickx L, Wu A, Théodoly O, Limozin L, Hamon Y, Puech PH, Controlling T cells spreading, mechanics and activation by micropatterning. Sci Rep 2021 Mar; 11(1): 6783.
2021
Cheng-Rui Qian, Fan Xia, Anne-Marie Sartre, Anthony Formisano, Sébastian Jaeger, Jacques A Nunès, ..., A critical regulatory role for the cytoplasmic domain of CD28 in ligand binding in naive T cells, <i>Science Bulletin</i>, In press, <a target="_blank" href="https://dx.doi.org/10.1016/j.scib.2020.08.007">⟨10.1016/j.scib.2020.08.007⟩</a>.
2020
Mailfert S, Wojtowicz K, Brustlein S, Blaszczak E, Bertaux N, Łukaszewicz M, Marguet D, Trombik T, Spot Variation Fluorescence Correlation Spectroscopy for Analysis of Molecular Diffusion at the Plasma Membrane of Living Cells. J Vis Exp 2020 Nov; (165): .
2020
Chouaki Benmansour N, Ruminski K, Sartre AM, Phelipot MC, Salles A, Bergot E, Wu A, Chicanne G, Fall..., Author Correction: Phosphoinositides regulate the TCR/CD3 complex membrane dynamics and activation. Sci Rep 2020 Jul; 10(1): 12558.
2020
Wu A, Wojtowicz K, Savary S, Hamon Y, Trombik T, Do ABC transporters regulate plasma membrane organism? Cell Mol Biol Lett 2020; 25(): 37.
2019
Sarri B, Canonge R, Audier X, Simon E, Wojak J, Caillol F, Cador C, Marguet D, Poizat F, Giovannini ..., Fast stimulated Raman and second harmonic generation imaging for intraoperative gastrointestinal cancer detection. Sci Rep 2019 Jul; 9(1): 10052.
2018
Dejardin MJ, Hemmerle A, Sadoun A, Hamon Y, Puech PH, Sengupta K, Limozin L, Lamellipod Reconstruction by Three-Dimensional Reflection Interference Contrast Nanoscopy (3D-RICN). Nano Lett 2018 Oct; 18(10): 6544-6550.
2018
Mailfert S, Touvier J, Benyoussef L, Fabre R, Rabaoui A, Blache MC, Hamon Y, Brustlein S, Monneret S..., A Theoretical High-Density Nanoscopy Study Leads to the Design of UNLOC, a Parameter-free Algorithm., Biophys J 2018 Aug; 115(3): 565-576.
2018
Scotté C, de Aguiar HB, Marguet D, Green EM, Bouzy P, Vergnole S, Winlove CP, Stone N, Rigneault H, Assessment of Compressive Raman versus Hyperspectral Raman for Microcalcification Chemical Imaging., Anal Chem 2018 Jun; 90(12): 7197-7203.
2018
Wang R, Brustlein S, Mailfert S, Fabre R, Fallet M, Sivankutty S, Rigneault H, Marguet D, A straightforward STED-background corrected fitting model for unbiased STED-FCS analyses. Methods 2018 May; 140-141(): 212-222.
2018
Nassima Chouaki-Benmansour, Kilian Ruminski, Anne-Marie Sartre, Marie-Claire Phelipot, Audrey Salles..., Phosphoinositides regulate the TCR/CD3 complex membrane dynamics and activation, <i>Scientific Reports</i>, 2018, 8 (1), pp.4966. <a target="_blank" href="https://dx.doi.org/10.1038/s41598-018-23109-8">⟨10.1038/s41598-018-23109-8⟩</a>.
2018
Xia F, Qian CR, Xun Z, Hamon Y, Sartre AM, Formisano A, Mailfert S, Phelipot MC, Billaudeau C, Jaege..., TCR and CD28 Concomitant Stimulation Elicits a Distinctive Calcium Response in Naive T Cells. Front Immunol 2018; 9(): 2864.
2017
Nardecchia I, Lechelon M, Gori M, Donato I, Preto J, Floriani E, Jaeger S, Mailfert S, Marguet D, Fe..., Detection of long-range electrostatic interactions between charged molecules by means of fluorescence correlation spectroscopy. Phys Rev E 2017 Aug; 96(2-1): 022403.
2017
Hamon Y, Blouin CM, Lamaze C, He HT, [Molecular and membrane dynamics of the gamma interferon receptor: just one more sugar!]. Med Sci (Paris) 2017; 33(8-9): 707-710.
2017
Mailfert S, Hamon Y, Bertaux N, He HT, Marguet D, A user's guide for characterizing plasma membrane subdomains in living cells by spot variation fluorescence correlation spectroscopy. Methods Cell Biol 2017; 139(): 1-22.
2016
Li K, Xiang X, Sun J, He HT, Wu J, Wang Y, Zhu C, Imaging Spatiotemporal Activities of ZAP-70 in Live T Cells Using a FRET-Based Biosensor. Ann Biomed Eng 2016 Dec; 44(12): 3510-3521.
2016
Blouin CM, Hamon Y, Gonnord P, Boularan C, Kagan J, Viaris de Lesegno C, Ruez R, Mailfert S, Bertaux..., Glycosylation-Dependent IFN-γR Partitioning in Lipid and Actin Nanodomains Is Critical for JAK Activation. Cell 2016 Aug; 166(4): 920-934.
2015
Baffou G, Rigneault H, Marguet D, Jullien L, Reply to: “Validating subcellular thermal changes revealed by fluorescent thermosensors” and “The 10(5) gap issue between calculation and measurement in single-cell thermometry”. Nat Methods 2015 Sep; 12(9): 803.
2014
Baffou G, Rigneault H, Marguet D, Jullien L, A critique of methods for temperature imaging in single cells. Nat Methods 2014 Sep; 11(9): 899-901.
2014
Julien Savatier, Sherazade Aknoun, Pierre Bon, Abdeladim L, Didier Marguet, Benoit Wattellier, Serge..., Dry mass and cell cycle follow-up from quantitative phase imaging, 12th European Congress on Digital Pathology , Jun 2014, Paris, France.
2014
Rouger V, Bordet G, Couillault C, Monneret S, Mailfert S, Ewbank JJ, Pujol N, Marguet D, Independent synchronized control and visualization of interactions between living cells and organisms. Biophys J 2014 May; 106(10): 2096-104.
2014
Marquèze-Pouey B, Mailfert S, Rouger V, Goaillard JM, Marguet D, Physiological epidermal growth factor concentrations activate high affinity receptors to elicit calcium oscillations. PLoS One 2014; 9(9): e106803.
2013
Rainy N, Chetrit D, Rouger V, Vernitsky H, Rechavi O, Marguet D, Goldstein I, Ehrlich M, Kloog Y, H-Ras transfers from B to T cells via tunneling nanotubes. Cell Death Dis 2013 Jul; 4(7): e726.
2013
Billaudeau C, Mailfert S, Trombik T, Bertaux N, Rouger V, Hamon Y, He HT, Marguet D, Probing the plasma membrane organization in living cells by spot variation fluorescence correlation spectroscopy. Methods Enzymol 2013; 519(): 277-302.
2013
Salles A, Billaudeau C, Sergé A, Bernard AM, Phélipot MC, Bertaux N, Fallet M, Grenot P, Marguet D..., Barcoding T cell calcium response diversity with methods for automated and accurate analysis of cell signals (MAAACS). PLoS Comput Biol 2013; 9(9): e1003245.
2012
Rouger V, Bertaux N, Trombik T, Mailfert S, Billaudeau C, Marguet D, Sergé A, Mapping molecular diffusion in the plasma membrane by Multiple-Target Tracing (MTT). J Vis Exp 2012 May; (63): e3599.
2012
He HT, Bongrand P, Membrane dynamics shape TCR-generated signaling. Front Immunol 2012;3():90.
2011
Xiang X, Sun J, Wu J, He HT, Wang Y, Zhu C, A FRET-Based Biosensor for Imaging SYK Activities in Living Cells. Cell Mol Bioeng 2011 Dec; 4(4): 670-677.
2011
Kress A, Ferrand P, Rigneault H, Trombik T, He HT, Marguet D, Brasselet S, Probing orientational behavior of MHC class I proteins and lipid probes in cell membranes by fluorescence polarization-resolved imaging. Biophys J 2011 Jul; 101(2): 468-76.
2011
Malissen B, Marguet D, Last but not least., Nat Immunol 2011 Jun; 12(7): 592-3.
2011
Brustlein S, Berto P, Hostein R, Ferrand P, Billaudeau C, Marguet D, Muir A, Knight J, Rigneault H, Double-clad hollow core photonic crystal fiber for coherent Raman endoscope., Opt Express 2011 Jun; 19(13): 12562-8.
2011
Ruprecht V, Wieser S, Marguet D, Schütz GJ, Spot variation fluorescence correlation spectroscopy allows for superresolution chronoscopy of confinement times in membranes. Biophys J 2011 Jun; 100(11): 2839-45.
2011
Brustlein S, Ferrand P, Walther N, Brasselet S, Billaudeau C, Marguet D, Rigneault H, Optical parametric oscillator-based light source for coherent Raman scattering microscopy: practical overview., J Biomed Opt 2011 Feb; 16(2): 021106.
2011
Julien Savatier, Pierre Bon, Didier Marguet, Serge Monneret, Correlative microscopy of living cells between fluorescence and quantitative phase imaging with a high resolution wavefront sensor, Biophysical Society 55th Annual Meeting , 2011, Baltimore, United States.
2011
He HT, Marguet D, Detecting nanodomains in living cell membrane by fluorescence correlation spectroscopy. Annu Rev Phys Chem 2011; 62(): 417-36.
2011
Pierre Bon, Julien Savatier, Benoit Wattelier, Didier Marguet, Serge Monneret, Quadriwave lateral shearing interferometry for quantitative phase microscopy: correlation with fluorescence measurements, <i>BIOS, Photonics West 2011, Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XVIII</i>, 2011, France. pp.79040P, <a target="_blank" href="https://dx.doi.org/10.1117/12.873177">⟨10.1117/12.873177⟩</a>.
2011
Julien Savatier, Pierre Bon, Didier Marguet, Serge Monneret, Simultaneous fluorescence and quantitative phase imaging of living cells with a high resolution wavefront sensor on a conventional microscope, Focus on Microscopy 2011 , 2011, Konstanz, Germany.
2011
Sophie Guia, Baptiste N Jaeger, Stefan Piatek, Sébastien Mailfert, Tomasz Trombik, Aurore Fenis, Ni..., Confinement of activating receptors at the plasma membrane controls natural killer cell tolerance. <i>Science Signaling</i>, 2011, 4 (167), pp.ra21. <a target="_blank" href="https://dx.doi.org/10.1126/scisignal.2001608">⟨10.1126/scisignal.2001608⟩</a>.
2010
Guardiola-Serrano F, Rossin A, Cahuzac N, Lückerath K, Melzer I, Mailfert S, Marguet D, Zörnig M, ..., Palmitoylation of human FasL modulates its cell death-inducing function. Cell Death Dis 2010 Oct; 1(10): e88.
2010
Rossin A, Kral R, Lounnas N, Chakrabandhu K, Mailfert S, Marguet D, Hueber AO, Identification of a lysine-rich region of Fas as a raft nanodomain targeting signal necessary for Fas-mediated cell death. Exp Cell Res 2010 May; 316(9): 1513-22.
2010
Pierre Bon, Julien Savatier, Didier Marguet, Benoit Wattelier, Serge Monneret, Quantitative phase contrast, refractive index anisotropy measurement, GdR Ondes Day , 2010, Marseille, France.
2010
Pierre Bon, Benoit Wattelier, Serge Monneret, Didier Marguet, Quantitative phase microscopy by QWLSI wavefront sensing: applications to long-duration imaging, BIOS, Photonics West 2010, Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XVII , Jan 2010, San Francisco, United States. pp.75700E.
2009
Pierre Bon, Serge Monneret, Didier Marguet, Benoit Wattelier, Quantitative phase contrast imaging using a SID4-HR wavefront sensor, ISS/Cerimed workshop, 5th thematic workshop on stem cells imaging , Dec 2009, Marseille, France.
2009
Serge Monneret, Pierre Bon, Benoit Wattelier, Didier Marguet, Quantitative phase microscopy using a high resolution wavefront sensor, Second Japanese-French workshop together with the first American-French meeting on Nanobiophotonics , Oct 2009, Marseille, France.
2009
Ferrand P, Pianta M, Kress A, Aillaud A, Rigneault H, Marguet D, A versatile dual spot laser scanning confocal microscopy system for advanced fluorescence correlation spectroscopy analysis in living cells. Rev Sci Instrum 2009 Aug; 80(8): 083702.
2009
Taïeb N, Maresca M, Guo XJ, Garmy N, Fantini J, Yahi N, The first extracellular domain of the tumor stem cell marker CD133 contains an antigenic ganglioside-binding motif. Cancer Lett 2009 Jun; 278(2): 164-173.
2009
Zarubica A, Plazzo AP, Stöckl M, Trombik T, Hamon Y, Müller P, Pomorski T, Herrmann A, Chimini G, Functional implications of the influence of ABCA1 on lipid microenvironment at the plasma membrane: a biophysical study. FASEB J 2009 Jun; 23(6): 1775-85.
2009
Pierre Bon, Serge Monneret, Benoit Wattelier, Didier Marguet, Quantitative phase microscopy using a high-resolution wavefront sensor, Focus on Microscopy 2009 , Apr 2009, Krakow, Poland.
2008
Chakrabandhu K, Huault S, Garmy N, Fantini J, Stebe E, Mailfert S, Marguet D, Hueber AO, The extracellular glycosphingolipid-binding motif of Fas defines its internalization route, mode and outcome of signals upon activation by ligand. Cell Death Differ 2008 Dec; 15(12): 1824-37.
2008
Lenne PF, Rigneault H, Marguet D, Wenger J, Fluorescence fluctuations analysis in nanoapertures: physical concepts and biological applications. Histochem Cell Biol 2008 Nov; 130(5): 795-805.
2008
Lasserre R, Guo XJ, Conchonaud F, Hamon Y, Hawchar O, Bernard AM, Soudja SM, Lenne PF, Rigneault H, ..., Raft nanodomains contribute to Akt/PKB plasma membrane recruitment and activation. Nat Chem Biol 2008 Sep; 4(9): 538-47.
2008
R. Lasserre, Xj Guo, F. Conchonaud, Y. Hamon, O. Hawchar, Am Bernard, Sm Soudja, Pierre-Francois Len..., Raft nanodomains contribute to Akt/PKB plasma membrane recruitment and activation, Nature Chemical Biology , 2008, 4 (9), pp.538-47.
2008
Sergé A, Bertaux N, Rigneault H, Marguet D, Dynamic multiple-target tracing to probe spatiotemporal cartography of cell membranes. Nat Methods 2008 Aug; 5(8): 687-94.
2008
He HT, Marguet D, T-cell antigen receptor triggering and lipid rafts: a matter of space and time scales. Talking Point on the involvement of lipid rafts in T-cell activation. EMBO Rep 2008 Jun; 9(6): 525-30.
2008
Randriamampita C, Mouchacca P, Malissen B, Marguet D, Trautmann A, Lellouch AC, A novel ZAP-70 dependent FRET based biosensor reveals kinase activity at both the immunological synapse and the antisynapse. PLoS One 2008 Jan; 3(1): e1521.
2008
Mugnier B, Nal B, Verthuy C, Boyer C, Lam D, Chasson L, Nieoullon V, Chazal G, Guo XJ, He HT, Rueff-..., Coronin-1A links cytoskeleton dynamics to TCR alpha beta-induced cell signaling. PLoS One 2008;3(10):e3467.
2007
Conchonaud F, Nicolas S, Amoureux MC, Ménager C, Marguet D, Lenne PF, Rougon G, Matarazzo V, Polysialylation increases lateral diffusion of neural cell adhesion molecule in the cell membrane. J Biol Chem 2007 Sep; 282(36): 26266-74.
2007
Fabien Conchonaud, Stéphane Nicolas, Marie-Claude Amoureux, Céline Ménager, Didier Marguet, Pierr..., Polysialylation increases lateral diffusion of neural cell adhesion molecule in the cell membrane. <i>Journal of Biological Chemistry</i>, 2007, Epub ahead of print. <a target="_blank" href="https://dx.doi.org/10.1074/jbc.M608590200">⟨10.1074/jbc.M608590200⟩</a>.
2007
Federico Belloni, Serge Monneret, Fabien Conchonaud, Didier Marguet, Hervé Rigneault, Holographic optical tweezers for the control of local stimulation of cell membranes, Horizons of Optics , Jul 2007, Grenoble, France.
2007
Serge Monneret, Federico Belloni, Fabien Conchonaud, Didier Marguet, Fluorescence microscopy of individual biological cell membranes stimulated by holographic optical tweezers, 10th conference of the French Society of Microscopies , June 2007, Grenoble, France.
2007
Vera Preller, Annegret Gerber, Sabine Wrenger, Mauro Togni, Didier Marguet, Janine Tadje, Uwe Lendec..., TGF-beta1-mediated control of central nervous system inflammation and autoimmunity through the inhibitory receptor CD26. Journal of Immunology , 2007, 178 (7), pp.4632-40.
2007
Preller V, Gerber A, Wrenger S, Togni M, Marguet D, Tadje J, Lendeckel U, Röcken C, Faust J, Neuber..., TGF-beta1-mediated control of central nervous system inflammation and autoimmunity through the inhibitory receptor CD26. J Immunol 2007 Apr; 178(7): 4632-40.
2007
Wenger J, Conchonaud F, Dintinger J, Wawrezinieck L, Ebbesen TW, Rigneault H, Marguet D, Lenne PF, Diffusion analysis within single nanometric apertures reveals the ultrafine cell membrane organization. Biophys J 2007 Feb; 92(3): 913-9.
2007
Chakrabandhu K, Hérincs Z, Huault S, Dost B, Peng L, Conchonaud F, Marguet D, He HT, Hueber AO, Palmitoylation is required for efficient Fas cell death signaling. EMBO J 2007 Jan; 26(1): 209-20.
2007
Arnaud Sergé, Nicolas Bertaux, Hervé Rigneault, Didier Marguet, Improved single molecular detection and tracing algorithms for the generation of a dynamic map of membrane diffusion in living cells, 51st Biophysical Society Annual Meeting , Jan 2007, Baltimore, United States.
2006
Hamon Y, Trompier D, Ma Z, Venegas V, Pophillat M, Mignotte V, Zhou Z, Chimini G, Cooperation between engulfment receptors: the case of ABCA1 and MEGF10. PLoS One 2006 Dec; 1(1): e120.
2006
Wenger J, Gérard D, Lenne PF, Rigneault H, Dintinger J, Ebbesen TW, Boned A, Conchonaud F, Marguet ..., Dual-color fluorescence cross-correlation spectroscopy in a single nanoaperture: towards rapid multicomponent screening at high concentrations. Opt Express 2006 Dec; 14(25): 12206-16.
2006
Federico Belloni, Serge Monneret, Fabien Conchonaud, Didier Marguet, Cells handling via interactive holographic optical tweezers, EOS Topical Meeting on Biophotonics and Biomedical Optics , Oct 2006, Paris, France.
2006
Didier Marguet, [Photonic revolution or how nonlinear optics fosters new approaches in cell and tissue imaging], Medicine/Sciences , 2006, 22 (10), pp.787.
2006
Djaker N, Marguet D, Rigneault H, [Stimulated Raman microscopy (CARS): From principles to applications]. Med Sci (Paris) 2006 Oct; 22(10): 853-8.
2006
Marguet D, Galli T, [Photonic revolution or how nonlinear optics fosters new approaches in cell and tissue imaging]. Med Sci (Paris) 2006 Oct; 22(10): 787.
2006
He HT, Gürsoy RN, Kupczyk-Subotkowska L, Tian J, Williams T, Siahaan TJ, Synthesis and chemical stability of a disulfide bond in a model cyclic pentapeptide: cyclo(1,4)-Cys-Gly-Phe-Cys-Gly-OH., J Pharm Sci 2006 Oct; 95(10): 2222-34.
2006
P.-F. Lenne, L. Wawrezinieck, F. Conchonaud, O. Wurtz, A. Boned, X.-J. Guo, H. Rigneault, H.-T. Hey, ..., Confined diffusion in the plasma membrane: Evidence for the respective role of lipid microdomains and the cytoskeleton, 20th National Congress of Cell Biology , Sep 2006, Anglet, France.
2006
Malika El Yacoubi, Jean-Marie Vaugeois, Didier Marguet, Nicole Sauze, Régis Guieu, Jean Costentin, ..., Behavioral characterization of CD26 deficient mice in animal tests of anxiety and antidepressant-like activity. <i>Behavioral Brain Research</i>, 2006, 171 (2), pp.279-85. <a target="_blank" href="https://dx.doi.org/10.1016/j.bbr.2006.04.003">⟨10.1016/j.bbr.2006.04.003⟩</a>.
2006
El Yacoubi M, Vaugeois JM, Marguet D, Sauze N, Guieu R, Costentin J, Fenouillet E, Behavioral characterization of CD26 deficient mice in animal tests of anxiety and antidepressant-like activity. Behav Brain Res 2006 Aug; 171(2): 279-85.
2006
Marguet D, Lenne PF, Rigneault H, He HT, Dynamics in the plasma membrane: how to combine fluidity and order. EMBO J 2006 Aug; 25(15): 3446-57.
2006
Lenne PF, Wawrezinieck L, Conchonaud F, Wurtz O, Boned A, Guo XJ, Rigneault H, He HT, Marguet D, Dynamic molecular confinement in the plasma membrane by microdomains and the cytoskeleton meshwork. EMBO J 2006 Jul; 25(14): 3245-56.
2006
Trompier D, Alibert M, Davanture S, Hamon Y, Pierres M, Chimini G, Transition from dimers to higher oligomeric forms occurs during the ATPase cycle of the ABCA1 transporter. J Biol Chem 2006 Jul; 281(29): 20283-90.
2006
Garmy N, Guo XJ, Taïeb N, Tourrès C, Tamalet C, Fantini J, Yahi N, Cellular isoform of the prion protein PrPc in human intestinal cell lines: genetic polymorphism at codon 129, mRNA quantification and protein detection in lipid rafts. Cell Biol Int 2006 Jun; 30(6): 559-67.
2006
Popovici C, Fallet M, Marguet D, Birnbaum D, Roubin R, Intracellular trafficking of LET-756, a fibroblast growth factor of C. elegans, is controlled by a balance of export and nuclear signals. Exp Cell Res 2006 May; 312(9): 1484-95.
2006
Cahuzac N, Baum W, Kirkin V, Conchonaud F, Wawrezinieck L, Marguet D, Janssen O, Zörnig M, Hueber A..., Fas ligand is localized to membrane rafts, where it displays increased cell death-inducing activity. Blood 2006 Mar; 107(6): 2384-91.
2006
Lapaque N, Forquet F, de Chastellier C, Mishal Z, Jolly G, Moreno E, Moriyon I, Heuser JE, He HT, Go..., Characterization of Brucella abortus lipopolysaccharide macrodomains as mega rafts. Cell Microbiol 2006 Feb; 8(2): 197-206.
2006
Guieu R, Fenouillet E, Devaux C, Fajloun Z, Carrega L, Sabatier JM, Sauze N, Marguet D, CD26 modulates nociception in mice via its dipeptidyl-peptidase IV activity. Behav Brain Res 2006 Jan; 166(2): 230-5.
2006
Wenger J, Rigneault H, Dintinger J, Marguet D, Lenne PF, Single-fluorophore diffusion in a lipid membrane over a subwavelength aperture. J Biol Phys 2006 Jan; 32(1): SN1-4.
2006
Preller V, Gerber A, Togni M, Wrenger S, Schraven B, Röcken C, Marguet D, Ansorge S, Brocke S, Rein..., CD26/DP IV in T cell activation and autoimmunity. Adv Exp Med Biol 2006; 575(): 187-93.
2006
N. Garmy, X.-J. Guo, N. Taïeb, C. Tourres, C. Tamalet, J. Fantini, N. Yahi, Cellular isoform of the prion protein PrP(c) in human intestinal cell lines: Genetic polymorphism at codon 129, mRNA quantification and protein detection in lipid rafts., Cell biology international. , 2006, 30, pp.559-67.
2005
Wawrezinieck L, Rigneault H, Marguet D, Lenne PF, Fluorescence correlation spectroscopy diffusion laws to probe the submicron cell membrane organization. Biophys J 2005 Dec; 89(6): 4029-42.
2005
Alder-Baerens N, Müller P, Pohl A, Korte T, Hamon Y, Chimini G, Pomorski T, Herrmann A, Headgroup-specific exposure of phospholipids in ABCA1-expressing cells. J Biol Chem 2005 Jul; 280(28): 26321-9.
2005
Hai-Tao He, Annemarie Lellouch, Didier Marguet, Lipid rafts and the initiation of T cell receptor signaling. <i>Seminars in Immunology</i>, 2005, 17 (1), pp.23-33. <a target="_blank" href="https://dx.doi.org/10.1016/j.smim.2004.09.001">⟨10.1016/j.smim.2004.09.001⟩</a>.
2005
He HT, Lellouch A, Marguet D, Lipid rafts and the initiation of T cell receptor signaling. Semin Immunol 2005 Feb; 17(1): 23-33.
2004
Lelouard H, Ferrand V, Marguet D, Bania J, Camosseto V, David A, Gatti E, Pierre P, Dendritic cell aggresome-like induced structures are dedicated areas for ubiquitination and storage of newly synthesized defective proteins. J Cell Biol 2004 Mar; 164(5): 667-75.
2004
Bonello G, Blanchard N, Montoya MC, Aguado E, Langlet C, He HT, Nunez-Cruz S, Malissen M, Sanchez-Ma..., Dynamic recruitment of the adapter protein LAT: LAT exists in two distinct intracellular pools and controls its own recruitment. J Cell Sci 2004 Mar; 117(Pt 7): 1009-16.
2004
Nal B, Carroll P, Mohr E, Verthuy C, Da Silva MI, Gayet O, Guo XJ, He HT, Alcover A, Ferrier P, Coronin-1 expression in T lymphocytes: insights into protein function during T cell development and activation. Int Immunol 2004 Feb; 16(2): 231-40.
2003
Yan S, Marguet D, Dobers J, Reutter W, Fan H, Deficiency of CD26 results in a change of cytokine and immunoglobulin secretion after stimulation by pokeweed mitogen. Eur J Immunol 2003 Jun; 33(6): 1519-27.
2003
Seddi R, Chaix JC, Puigserver A, Guo XJ, Expression of a soluble and activatable form of bovine procarboxypeptidase A in Escherichia coli. Protein Expr Purif 2003 Feb; 27(2): 220-8.
2003
Fan H, Yan S, Stehling S, Marguet D, Schuppaw D, Reutter W, Dipeptidyl peptidase IV/CD26 in T cell activation, cytokine secretion and immunoglobulin production. Adv Exp Med Biol 2003; 524(): 165-74.
2002
Hamon Y, Chambenoit O, Chimini G, ABCA1 and the engulfment of apoptotic cells. Biochim Biophys Acta 2002 Dec; 1585(2-3): 64-71.
2002
Rigot V, Hamon Y, Chambenoit O, Alibert M, Duverger N, Chimini G, Distinct sites on ABCA1 control distinct steps required for cellular release of phospholipids. J Lipid Res 2002 Dec; 43(12): 2077-86.
2002
Attie AD, Hamon Y, Brooks-Wilson AR, Gray-Keller MP, MacDonald ML, Rigot V, Tebon A, Zhang LH, Mulli..., Identification and functional analysis of a naturally occurring E89K mutation in the ABCA1 gene of the WHAM chicken., J Lipid Res 2002 Oct; 43(10): 1610-7.
2002
Marguet D, Chimini G, The ABCA1 transporter and ApoA-I: obligate or facultative partners? Trends Cardiovasc Med 2002 Oct; 12(7): 294-8.
2002
Aguado E, Richelme S, Nuñez-Cruz S, Miazek A, Mura AM, Richelme M, Guo XJ, Sainty D, He HT, Malisse..., Induction of T helper type 2 immunity by a point mutation in the LAT adaptor., Science 2002 Jun; 296(5575): 2036-40.
2002
Drevot P, Langlet C, Guo XJ, Bernard AM, Colard O, Chauvin JP, Lasserre R, He HT, TCR signal initiation machinery is pre-assembled and activated in a subset of membrane rafts. EMBO J 2002 Apr; 21(8): 1899-908.
2002
Hueber AO, Bernard AM, Herincs Z, Couzinet A, He HT, An essential role for membrane rafts in the initiation of Fas/CD95-triggered cell death in mouse thymocytes. EMBO Rep 2002 Feb; 3(2): 190-6.
2002
Montoya MC, Sancho D, Bonello G, Collette Y, Langlet C, He HT, Aparicio P, Alcover A, Olive D, Sánc..., Role of ICAM-3 in the initial interaction of T lymphocytes and APCs. Nat Immunol 2002 Feb; 3(2): 159-68.
2002
Wang M, Gorrell MD, Abbott CA, Jaggi R, Marguet D, Dickinson RG, Hepatic covalent adduct formation with zomepirac in the CD26-deficient mouse. J Gastroenterol Hepatol 2002 Jan; 17(1): 66-71.
2001
Chambenoit O, Hamon Y, Marguet D, Rigneault H, Rosseneu M, Chimini G, Specific docking of apolipoprotein AI at the cell surface requires a functional ABCA1 transporter. J Biol Chem 2001 Mar; 276(13): 9955-60.
2000
Hamon Y, Broccardo C, Chambenoit O, Luciani MF, Toti F, Chaslin S, Freyssinet JM, Devaux PF, McNeish..., ABC1 promotes engulfment of apoptotic cells and transbilayer redistribution of phosphatidylserine. Nat Cell Biol 2000 Jul; 2(7): 399-406.
2000
Marguet D, Baggio L, Kobayashi T, Bernard AM, Pierres M, Nielsen PF, Ribel U, Watanabe T, Drucker DJ..., Enhanced insulin secretion and improved glucose tolerance in mice lacking CD26. Proc Natl Acad Sci USA 2000 Jun; 97(12): 6874-9.
2000
Langlet C, Bernard AM, Drevot P, He HT, Membrane rafts and signaling by the multichain immune recognition receptors. Curr Opin Immunol 2000 Jun; 12(3): 250-5.
2000
Ilangumaran S, He HT, Hoessli DC, Microdomains in lymphocyte signaling: beyond GPI-anchored proteins. Immunol Today 2000 Jan; 21(1): 2-7.
1999
Marguet D, Luciani MF, Moynault A, Williamson P, Chimini G, Engulfment of apoptotic cells involves the redistribution of membrane phosphatidylserine on phagocyte and prey. Nat Cell Biol 1999 Nov; 1(7): 454-6.
1999
Marguet D, Spiliotis ET, Pentcheva T, Lebowitz M, Schneck J, Edidin M, Lateral diffusion of GFP-tagged H2Ld molecules and of GFP-TAP1 reports on the assembly and retention of these molecules in the endoplasmic reticulum. Immunity 1999 Aug; 11(2): 231-40.
1999
Raphel V, Giardina T, Guevel L, Perrier J, Dupuis L, Guo XJ, Puigserver A, Cloning, sequencing and further characterization of acylpeptide hydrolase from porcine intestinal mucosa. Biochim Biophys Acta 1999 Jul; 1432(2): 371-81.
1999
Ardouin L, Boyer C, Gillet A, Trucy J, Bernard AM, Nunes J, Delon J, Trautmann A, He HT, Malissen B,..., Crippling of CD3-zeta ITAMs does not odd T cell receptor signaling. Immunity 1999 Apr; 10(4): 409-20.
1999
Darnis S, Judge N, Guo XJ, Marchis-Mouren G, Puigserver A, Chaix JC, Molecular cloning and primary structure analysis of porcine pancreatic alpha-amylase. Biochim Biophys Acta 1999 Mar; 1430(2): 281-9.
1999
Lebowitz MS, O'Herrin SM, Hamad AR, Fahmy T, Marguet D, Barnes NC, Pardoll D, Bieler JG, Schneck JP, Soluble, high-affinity dimers of T-cell receptors and class II major histocompatibility complexes: biochemical probes for analysis and modulation of immune responses. Cell Immunol 1999 Mar; 192(2): 175-84.
1999
Darnis S, Judge N, Marino C, Avilés FX, Puigserver A, Chaix JC, Guo XJ, Cloning, sequencing and functional expression of a cDNA encoding porcine pancreatic preprocarboxypeptidase A1. Eur J Biochem 1999 Feb; 259(3): 719-25.
1998
Beissert S, He HT, Hueber AO, Lellouch AC, Metze D, Mehling A, Luger TA, Schwarz T, Grabbe S, Impaired cutaneous immune responses in Thy-1-deficient mice. J Immunol 1998 Nov; 161(10): 5296-302.
1998
David L, Guo XJ, Villard C, Moulin A, Puigserver A, Purification and molecular cloning of porcine intestinal glycerol-ester hydrolase–evidence for its identity with carboxylesterase. Eur J Biochem 1998 Oct; 257(1): 142-8.
1998
Montixi C, Langlet C, Bernard AM, Thimonier J, Dubois C, Wurbel MA, Chauvin JP, Pierres M, He HT, Engagement of T cell receptor triggers its recruitment to low-density detergent-insoluble membrane domains. EMBO J 1998 Sep; 17(18): 5334-48.
1997
Hueber AO, Bernard AM, Battari CL, Marguet D, Massol P, Foa C, Brun N, Garcia S, Stewart C, Pierres ..., Thymocytes in Thy-1-/- mice show increased TCR signaling and impaired differentiation. Curr Biol 1997 Sep; 7(9): 705-8.
1997
Thimonier J, Montixi C, Chauvin JP, He HT, Rocca-Serra J, Barbet J, Thy-1 immunolabeled thymocyte microdomains studied with the atomic force microscope and the electron microscope. Biophys J 1997 Sep; 73(3): 1627-32.
1997
Guérin S, Mari B, Maulon L, Belhacène N, Marguet D, Auberger P, CD10 plays a specific role in early thymic development. FASEB J 1997 Apr; 11(5): 376-81.
1996
Olcese L, Lang P, Vély F, Cambiaggi A, Marguet D, Bléry M, Hippen KL, Biassoni R, Moretta A, Moret..., Human and mouse killer-cell inhibitory receptors recruit PTP1C and PTP1D protein tyrosine phosphatases. J Immunol 1996 Jun; 156(12): 4531-4.
1996
David F, Baricault L, Sapin C, Gallet X, Marguet D, Thomas-Soumarmon A, Trugnan G, Reduced cell surface expression of a mutated dipeptidyl peptidase IV (DPP IV/CD26) correlates with the generation of a beta strand in its C-terminal domain. Biochem Biophys Res Commun 1996 May; 222(3): 833-8.
1995
Golstein P, Marguet D, Depraetere V, Fas bridging cell death and cytotoxicity: the reaper connection. Immunol Rev 1995 Aug; 146(): 45-56.
1995
Golstein P, Marguet D, Depraetere V, Homology between reaper and the cell death domains of Fas and TNFR1. Cell 1995 Apr; 81(2): 185-6.
1994
Bernard AM, Mattei MG, Pierres M, Marguet D, Structure of the mouse dipeptidyl peptidase IV (CD26) gene., Biochemistry 1994 Dec; 33(50): 15204-14.
1994
Lazaro I, Naniche D, Signoret N, Bernard AM, Marguet D, Klatzmann D, Dragic T, Alizon M, Sattentau Q, Factors involved in entry of the human immunodeficiency virus type 1 into permissive cells: lack of evidence of a role for CD26. J Virol 1994 Oct; 68(10): 6535-46.
1994
Hueber AO, Pierres M, He HT, Quantitating apoptosis by a nonradioactive DNA dot blot assay. Anal Biochem 1994 Sep; 221(2): 431-3.
1994
Hueber AO, Raposo G, Pierres M, He HT, Thy-1 triggers mouse thymocyte apoptosis through a bcl-2-resistant mechanism. J Exp Med 1994 Mar; 179(3): 785-96.
1994
Hueber AO, Pierres M, He HT, Thy-1 functions as a recognition/signaling molecule during mouse T lymphocyte development. Braz J Med Biol Res 1994 Feb; 27(2): 275-81.
1993
Judge N, Søgaard M, Chaix JC, Martin-Eauclaire MF, Svensson B, Marchis-Mouren G, Guo XJ, Comparison of barley malt alpha-amylase isozymes 1 and 2: construction of cDNA hybrids by in vivo recombination and their expression in yeast. Gene 1993 Aug; 130(2): 159-66.
1993
David F, Bernard AM, Pierres M, Marguet D, Identification of serine 624, aspartic acid 702, and histidine 734 as the catalytic triad residues of mouse dipeptidyl-peptidase IV (CD26). A member of a novel family of nonclassical serine hydrolases. J Biol Chem 1993 Aug; 268(23): 17247-52.
1993
Malissen B, Wegener AM, Hoeveler A, Marguet D, Molecular dissection of the T-cell receptor/CD3 complex. Immunol Ser 1993; 59(): 29-40.
1992
Fantino E, Marguet D, Lauquin GJ, Downstream activating sequence within the coding region of a yeast gene: specific binding in vitro of RAP1 protein. Mol Gen Genet 1992 Dec; 236(1): 65-75.
1992
Hueber AO, Pierres M, He HT, Sulfated glycans directly interact with mouse Thy-1 and negatively regulate Thy-1-mediated adhesion of thymocytes to thymic epithelial cells. J Immunol 1992 Jun; 148(12): 3692-9.
1992
Darmoul D, Lacasa M, Baricault L, Marguet D, Sapin C, Trotot P, Barbat A, Trugnan G, Dipeptidyl peptidase IV (CD 26) gene expression in enterocyte-like colon cancer cell lines HT-29 and Caco-2. Cloning of the complete human coding sequence and changes of dipeptidyl peptidase IV mRNA levels during cell differentiation. J Biol Chem 1992 Mar; 267(7): 4824-33.
1992
Marguet D, Bernard AM, Vivier I, Darmoul D, Naquet P, Pierres M, cDNA cloning for mouse thymocyte-activating molecule. A multifunctional ecto-dipeptidyl peptidase IV (CD26) included in a subgroup of serine proteases. J Biol Chem 1992 Feb; 267(4): 2200-8.
1991
Vivier I, Marguet D, Naquet P, Bonicel J, Black D, Li CX, Bernard AM, Gorvel JP, Pierres M, Evidence that thymocyte-activating molecule is mouse CD26 (dipeptidyl peptidase IV). J Immunol 1991 Jul; 147(2): 447-54.
1991
Theveniau M, Guo XJ, Rage P, Rougon G, Removal of C6 astrocytoma cell surface molecules with phosphatidylinositol phospholipase C: effect on regulation of neural cell adhesion molecule isoforms. J Neurochem 1991 Jul; 57(1): 67-74.
1991
Rougon G, Alterman LA, Dennis K, Guo XJ, Kinnon C, The murine heat-stable antigen: a differentiation antigen expressed in both the hematolymphoid and neural cell lineages. Eur J Immunol 1991 Jun; 21(6): 1397-402.
1991
He HT, Naquet P, Caillol D, Pierres M, Thy-1 supports adhesion of mouse thymocytes to thymic epithelial cells through a Ca2(+)-independent mechanism. J Exp Med 1991 Feb; 173(2): 515-8.
1990
Reisine T, He HT, Rens-Domiano S, Martin JM, Raynor K, Borislow S, Thermos K, Biochemical properties of somatostatin receptors. Metabolism 1990 Sep; 39(9 Suppl 2): 70-3.
1990
Guo XJ, Fantini J, Roubin R, Marvaldi J, Rougon G, Evaluation of the effect of suramin on neural cell growth and N-CAM expression. Cancer Res 1990 Aug; 50(16): 5164-70.
1990
Gangloff SP, Marguet D, Lauquin GJ, Molecular cloning of the yeast mitochondrial aconitase gene (ACO1) and evidence of a synergistic regulation of expression by glucose plus glutamate. Mol Cell Biol 1990 Jul; 10(7): 3551-61.
1990
He HT, Rens-Domiano S, Martin JM, Law SF, Borislow S, Woolkalis M, Manning D, Reisine T, Solubilization of active somatostatin receptors from rat brain. Mol Pharmacol 1990 May; 37(5): 614-21.
1990
Fantini J, Guo XJ, Marvaldi J, Rougon G, Suramin inhibits proliferation of rat glioma cells and alters N-CAM cell surface expression. Int J Cancer 1990 Mar; 45(3): 554-61.
1990
Chimini G, Boretto J, Marguet D, Lanau F, Lauquin G, Pontarotti P, Molecular analysis of the human MHC class I region using yeast artificial chromosome clones. Immunogenetics 1990; 32(6): 419-26.
1989
He HT, Johnson K, Thermos K, Reisine T, Purification of a putative brain somatostatin receptor. Proc Natl Acad Sci USA 1989 Mar; 86(5): 1480-4.
1989
Thermos K, He HT, Wang HL, Margolis N, Reisine T, Biochemical properties of brain somatostatin receptors. Neuroscience 1989; 31(1): 131-41.
1988
Marguet D, Guo XJ, Lauquin GJ, Yeast gene SRP1 (serine-rich protein). Intragenic repeat structure and identification of a family of SRP1-related DNA sequences. J Mol Biol 1988 Aug; 202(3): 455-70.
1988
Marguet D, Fantino E, Lauquin GJ, Gene cloning from yeast chromosome-specific mini-library. Isolation of the SRP1-related DNA sequence located on chromosome XV. FEBS Lett 1988 Jul; 234(2): 421-5.
1987
He HT, Finne J, Goridis C, Biosynthesis, membrane association, and release of N-CAM-120, a phosphatidylinositol-linked form of the neural cell adhesion molecule. J Cell Biol 1987 Dec; 105(6 Pt 1): 2489-500.
1986
He HT, Barbet J, Chaix JC, Goridis C, Phosphatidylinositol is involved in the membrane attachment of NCAM-120, the smallest component of the neural cell adhesion molecule. EMBO J 1986 Oct; 5(10): 2489-94.
1986
Marguet D, Lauquin GJ, The yeast SRP gene: positive modulation by glucose of its transcriptional expression. Biochem Biophys Res Commun 1986 Jul; 138(1): 297-303.
1986
Gennarini G, Hirsch MR, He HT, Hirn M, Finne J, Goridis C, Differential expression of mouse neural cell-adhesion molecule (N-CAM) mRNA species during brain development and in neural cell lines. J Neurosci 1986 Jul; 6(7): 1983-90.
1985
Hirn M, Deagostini-Bazin H, Gennarini G, Santoni MJ, He HT, Hirsch MR, Goridis C, Structural and functional studies on N-CAM neural cell adhesion molecules. J Physiol (Paris) 1985; 80(4): 247-54.