CIML – Centre d'Immunologie de Marseille-Luminy

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The Center for Immunology of Marseille-Luminy (CIML) – Advancing immunology together

Founded in 1976, the CIML is an internationally renowned research center dedicated to the study of the immune system in all its diversity. Under the joint supervision of Aix-Marseille University, the CNRS, and Inserm, our institute embodies nearly 50 years of scientific excellence and innovation in immunology.

Join CIML as a Team Leader in Immunology!

The Center for Immunology of Marseille-Luminy (CIML) is celebrating 50 years of excellence and is now recruiting two new team […]

Bonne année 2026 !

Le CIML vous souhaite une année exceptionnelle, à l’image de celle qui s’annonce : nous célébrons nos 50 ans. 50 […]

Appel à projets

Réjane Rua obtient un ERC Consolidator Grant 2025 : une avancée majeure pour la compréhension de l’immunité cérébrale au CIML

Réjane Rua, chercheuse à l’Inserm au Centre d’Immunologie de Marseille-Luminy (CIML – Inserm/CNRS/Aix-Marseille Université), vient d’obtenir un ERC Consolidator Grant […]

News

Sophie Ugolini (Inserm / Temper Bio) distinguée au Palmarès des inventeurs Le Point 2026

Créé par le magazine Le Point, le Palmarès des inventeurs met en lumière chaque année les chercheurs, scientifiques et entrepreneurs […]

Les neurones sensoriels protègent les tissus contre les dommages inflammatoires lors d’infections virales

Une étude révèle comment le système nerveux sensoriel limite les effets délétères de l’inflammation sans compromettre l’élimination du virus Une […]

Join CIML as a Team Leader in Immunology!

The Center for Immunology of Marseille-Luminy (CIML) is celebrating 50 years of excellence and is now recruiting two new team […]

Bonne année 2026 !

Le CIML vous souhaite une année exceptionnelle, à l’image de celle qui s’annonce : nous célébrons nos 50 ans. 50 […]

Events

crowd of people sitting on chairs inside room

Nicolas GAUDENZIO, CIML external seminar

Nicolas Gaudenzio, Infinity – Toulouse

a group of people in graduation gowns holding their caps up

Pierre-Vincent BARBON, CIML thesis defense

Pierre-Vincent Barbon

group of people having a meeting

Alexandre DAVID, CIML external seminar

Alexandre David – IRCM – Montpellier

group of people having a meeting

Renaud LESOURNE, CIML external seminar

Renaud Lesourne, INFINITY, Toulouse

Latest Publications

Ngo C, Pierini-Malosse C, Rahmani K, Valente M, Collinet N, Bessou G, Guerry C, Fabregue M, Mathieu …, Plasmacytoid dendritic cells are dispensable or detrimental in murine systemic or respiratory viral infections., Nat Immunol 2025 Sep; (): .

Wang X, Li J, Rebuffet L, Cheng M, Bao B, Chen Y, Zheng X, Chen Y, Sun H, Sun R, Vivier E, Peng H, T…, Innate lymphoid cells originate from fetal liver-derived tissue-resident progenitors., Sci Immunol 2025 Jul; 10(109): eadu7962.

Mailfert S, Djendli M, Fabre R, Marguet D, Bertaux N, Quality control maps: Real-time quantitative control of single-molecule localization microscopy data., Biophys J 2025 Apr; 124(7): 1132-1145.

Jena KK, Mambu J, Boehmer D, Sposito B, Millet V, de Sousa Casal J, Muendlein HI, Spreafico R, Fenou…, Type III interferons induce pyroptosis in gut epithelial cells and impair mucosal repair., Cell 2024 Dec; 187(26): 7533-7550.e23.

Santamaria JC, Chevallier J, Dutour L, Picart A, Kergaravat C, Cieslak A, Amrane M, Vincentelli R, P…, RANKL treatment restores thymic function and improves T cell-mediated immune responses in aged mice., Sci Transl Med 2024 Dec; 16(776): eadp3171.

Borelli A, Santamaria JC, Zamit C, Apert C, Chevallier J, Pierre P, Argüello RJ, Spinelli L, Irla M, Lymphotoxin limits Foxp3+ regulatory T cell development from Foxp3lo precursors via IL-4 signaling., Nat Common 2024 Aug; 15(1): 6976.

Lucas Rebuffet, Janine E Melsen, Bertrand Escalière, Daniela Basurto-Lozada, Avinash Bhandoola, Nik…, High-dimensional single-cell analysis of human natural killer cell heterogeneity, <i>Nature Immunology</i>, 2024, 25 (8), pp.1474-1488. <a target="_blank" href="https://dx.doi.org/10.1038/s41590-024-01883-0">⟨10.1038/s41590-024-01883-0⟩</a>.

Offres d’emploi

Research Engineer

Research Engineer – Target plasmacytoid dendritic cell interferon responses to limit lung immunopathology during emerging respiratory viral infections (UNFIRE project)

Research Engineer

Research Engineer (IE) – Investigating the role of endosomal dynamic modulators during immune dysregulation and neurodegenerative pathology – IMPACT Sensors project