Publication: Interaction between GUVs and catanionic nanocontainers: new insight into spontaneous membrane fusion.

Publié dans: Chem Commun (Camb) 2012 Jul; 48(53): 6648-50

Auteurs: Mauroy C, Castagnos P, Blache MC, Teissié J, Rico-Lattes I, Rols MP, Blanzat M

Résumé

Spontaneous receptor-free membrane fusion with pure lipid systems, used as a cell membrane model, is demonstrated with easy-to-handle lactose-derived catanionic vesicles. This fusion, mediated and controlled by phospholipids, emphasizes the great value of these nanovesicles for enhanced direct cytosolic drug delivery without the shortcomings linked with endocytic pathways.

Lien vers Pubmed [PMID] – 22634609

Lien vers le DOI – 10.1039/c2cc32093b