Publication: How opportunistic agents benefit from viral infections: the plasmacytoid dendritic cell connection.

Publié dans: Cell Host Microbe 2008 Oct; 4(4): 305-7

Auteurs: Baranek T, Dalod M

Résumé

Plasmacytoid dendritic cells (pDCs) drive antiviral immunity through their rapid production of type I interferon (IFN-I). In this issue, Zuniga et al. (2008) report that both acute and persistent viral infections dramatically decrease pDC numbers and impair their capacity to produce IFN-I, leading to an enhanced susceptibility to opportunistic viruses.

Lien vers Pubmed [PMID] – 18854232

Lien vers le DOI – 10.1016/j.chom.2008.09.010