Distinct t(7;9)(q34;q32) breakpoints in healthy individuals and individuals with T-ALL.

Recherche

Thème

Dendritic cell responses to early murine cytomegalovirus infection: subset functional specialization and differential regulation by interferon alpha/beta.

Expression of a soluble and activatable form of bovine procarboxypeptidase A in Escherichia coli.

Publié dans: Nat Genet 2003 Mar; 33(3): 342-4

Auteurs: Marculescu R, Vanura K, Le T, Simon P, Jäger U, Nadel B

Résumé

After V(D)J-mediated translocations, signal joints are retained on one of the derivative chromosomes. We report here that such signal joints are highly reactive and constitute unstable genomic elements with potential oncogenic properties.

Lien vers Pubmed [PMID] – 12567187