Publication: Correction: The coenzyme A precursor pantethine enhances antitumor immunity in sarcoma.

Publié dans: Life Sci Alliance 2024 Feb; 7(2):

Auteurs: Miallot R, Millet V, Roger A, Fenouil R, Tardivel C, Martin JC, Tranchida F, Shintu L, Berchard P, Sousa Lanza J, Malissen B, Henri S, Ugolini S, Dutour A, Finetti P, Bertucci F, Blay JY, Galland F, Naquet P

Résumé

VitB5 level becomes limiting in sarcomas. It is regulated by the pantetheinase activity of VNN1. VNN1 expression in sarcomas is associated with better prognosis and immune infiltration. In mice, complementation with pantethine, a vitB5 precursor, boosts antitumor immunity.

Lien vers Pubmed [PMID] – 38030222

Lien vers le DOI – 10.26508/lsa.202302479